Multimerization of AAGTGA and GAAAGT generates sequences that mediate virus inducibility by mimicking an interferon promoter element.

Name: Multimerization of AAGTGA and GAAAGT generates sequences that mediate virus inducibility by mimicking an interferon promoter element.
Creator: National Academy of Sciences
Published: 1991-02-15T00:00:00+08:00

PubMed Central1991-02-15 更新2026-05-16 收录

病毒诱导转录调控

干扰素启动子元件

数据链接：

https://pmc.ncbi.nlm.nih.gov/articles/PMC51019/数据链接链接失效反馈

官方服务：

资源简介：

Multimeric AAGTGA and GAAAGT, when inserted before a minimal promoter, mediate virus-inducible transcription. We have determined that the active sequence within these multimers is TGAAAGTGAAAGT, which is structurally similar to GAGAAGTGAAAGT, a positive response element delineated in the beta-interferon gene promoter. Both sequences behave like protoenhancers and are similar as regards induction by virus or interferon regulatory factor 1 when supported by a simian virus 40 enhancer. IMAGES:

提供机构：

National Academy of Sciences

创建时间：

1991-02-15