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Cryo-EM structure of the proton coupled folate transporter at pH 6.0 bound to pemetrexed

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Protein Data Bank Japan2025-07-02 更新2026-03-21 收录
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Cryo-EM structure of the proton coupled folate transporter at pH 6.0 bound to pemetrexed Descriptor: 2-{4-[2-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-ETHYL]-BENZOYLAMINO}-PENTANEDIOIC ACID, Proton-coupled folate transporter, nanobody Authors: Parker, J.L, Deme, J.C, Lea, S.M, Newstead, S. Deposit date: 2020-12-18 Release date: 2021-05-12 Last modified: 2025-07-02 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Structural basis of antifolate recognition and transport by PCFT. Nature, 595, 2021
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2020-12-18
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