Neurtrophin-3 (NTF3, also known as NT-3) is the main ligand for the neuronal receptor tyrosine kinase NTRK3 (TRKC) (Lamballe et al. 1991). NTRK3 is not activated by other member of the neurotrophin fa
NTRK3 (TRKC), activated by NTF3 binding, trans-autophosphorylates on tyrosine residues in the intracellular domain (Urfer et al. 1995, Yuen and Mobley 1999, Huang and Reichardt 2001). Tyrosine residue
This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which al
We analyzed the copy number profiles of clinical samples of diagnostically difficult melanocytic tumors. Of 1202 cases, 22 cases demonstrated relative gain of the 5' portion of NTRK3. We further perf
