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Crystal structure of Trk-A in complex with the Pan-Trk Kinase Inhibitor, compound 10e

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Protein Data Bank Japan2023-11-22 更新2026-03-21 收录
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Crystal structure of Trk-A in complex with the Pan-Trk Kinase Inhibitor, compound 10e Descriptor: High affinity nerve growth factor receptor, N-{2-[({3-[6-(piperazin-1-yl)pyridin-3-yl]-1H-indazol-5-yl}amino)methyl]phenyl}methanesulfonamide Authors: Kensuke, A, Kazutaka, I. Deposit date: 2019-01-11 Release date: 2019-07-17 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.3 Å) Cite: The discovery of novel 3-aryl-indazole derivatives as peripherally restricted pan-Trk inhibitors for the treatment of pain. Bioorg.Med.Chem.Lett., 29, 2019
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2019-01-11
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