Interval running training improves age-related skeletal muscle wasting and bone loss: animal experiment in ovariectomized rats

Various
types of running training play an important role in the
prevention of age-related diseases, such as sarcopenia and osteoporosis.
However, among various types of running training, interval
running training affects age-related muscle wasting and bone loss, and its mechanisms are still unclear. This study was to clarify
its effect and mechanism in OVX-induced rat models.
Interval
running training could improve muscle growth and osteogenic differentiation by
enhancing the expression of BMPs and SIRTs in aging-induced OVX rats.
Therefore, the repetition of low and high intensities within a single
exercise bout, such as interval running training, may be
recommended for practical intervention to prevent skeletal muscle wasting and
bone loss in the elderly.