Cryo-EM structure of human rod CNGA1/B1 channel in L-cis-Diltiazem-blocked open state

Cryo-EM structure of human rod CNGA1/B1 channel in L-cis-Diltiazem-blocked open state Descriptor: (2R,3R)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate, CYCLIC GUANOSINE MONOPHOSPHATE, Cyclic nucleotide-gated cation channel beta-1, ... Authors: Xue, J, Han, Y, Jiang, Y. Deposit date: 2021-07-17 Release date: 2021-11-03 Last modified: 2025-05-14 Method: ELECTRON MICROSCOPY (2.88 Å) Cite: Structural mechanisms of assembly, permeation, gating, and pharmacology of native human rod CNG channel. Neuron, 110, 2022