PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane

At the plasma membrane, phosphatidylinositol-4-phosphate 5-kinase type-1 alpha (PIP5K1A) and beta (PIP5K1B) phosphorylate phosphatidylinositol 3-phosphate (PI3P) to phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2) (Tolias et al. 1998).

在质膜上，磷脂酰肌醇-4,5-二磷酸激酶1型α（PIP5K1A）和β（PIP5K1B）将磷脂酰肌醇-3-磷酸（PI3P）磷酸化生成磷脂酰肌醇-3,5-二磷酸（PI(3,5)P2)（Tolias等，1998年）。