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ena-DATASET-EMBL-06-12-2018-02:10:51:685-261 - samples

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https://www.omicsdi.org/dataset/ega/EGAD00001004499
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In this study, we aimed to identify somatic structural variation of T-cell acute lymphoblastic leukemias (T-ALLs_ from patient-derived xenografts (PDX) at the single-cell level. For this purpose, we performed strand-specific single-cell sequencing of PDX-derived T-ALL relapse samples from two juvenile patients (P1, P33). To validate structural variation detected via scTRIP, we profiled whole exome sequencing (WES) data from P33 (samples taken during initial disease, remission, relapse), and mate-pair sequencing data from P1 (relapse).EGA dataset EGAD00001004499
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2018-12-17
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