Mir17

ENCODES an ncrna that exhibits mRNA 3'-UTR binding (ortholog); mRNA base-pairing translational repressor activity (ortholog); INVOLVED IN negative regulation of ERK1 and ERK2 cascade; positive regulation of apoptotic process; positive regulation of endothelial cell proliferation; ASSOCIATED WITH acute myocardial infarction; Experimental Liver Cirrhosis; Hyperalgesia; FOUND IN extracellular exosome (ortholog); RISC complex (ortholog); INTERACTS WITH 2-acetamidofluorene; atrazine; bleomycin A2

编码一种展现出mRNA 3'-UTR结合（同源）特性的非编码RNA；具有mRNA碱基配对翻译抑制活性（同源）；参与ERK1和ERK2信号通路负调节；促进凋亡过程正调节；促进内皮细胞增殖正调节；与急性心肌梗死、实验性肝硬化和痛觉过敏相关；存在于细胞外囊泡（同源）、RISC复合体（同源）中；与2-乙酰氨基荧光素、 atrazine、bleomycin A2相互作用。