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Early commitment genes drive fast, irreversible commitment to human embryonic stem cell differentiation [scRNA-seq]

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NIAID Data Ecosystem2026-04-30 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP217261
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The goal of this study was to characterise transcriptional changes in single hESCs grown in a colony and treated with BMP4 to induce differentiation The goal of this study was to characterise transcriptional changes in single GATA3-/- hESCs grown in a colony and treated with BMP4 to induce differentiation Overall design: scRNA-Seq was performed on cultured hESCs grown in mTeSR1 with BMP4 for 48 hours. scRNA-Seq was performed on a cultured hESC GATA3-/- monoclonal cell line grown in mTeSR1 with BMP4 for 48 hours.
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2023-02-09
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