The Bxb1 bacteriophage serine DNA recombinase is an efficient tool for engineering recombinant DNA into the genomes of cultured cells. Generally, a single engineered “landing pad” site is introduced i
The Synthetic Yeast Genome Project (Sc2.0) represents the first foray into eukaryotic genome engineering and a novel framework for designing and building the next generation of industrial microbes. Ho
Use DNase-seq to assess genome-wide chromation remodeling which occurred in CRISPR/Cas9 and TALE genome engineering systems Overall design: Determining chromatin structural changes in transfected cell