Neuronal Methylome in Multiple Sclerosis. Neuronal Methylome in Multiple Sclerosis
收藏NIAID Data Ecosystem2026-03-10 收录
下载链接:
https://www.ncbi.nlm.nih.gov/bioproject/PRJNA489474
下载链接
链接失效反馈官方服务:
资源简介:
DNA methylation profiling of NeuN+sorted neuronal nuclei from post-mortem brain tissue of Multiple Sclerosis (MS) patients (n=10) (MS) and non-neurological controls (n=7) (non-MS). Genomic DNA was subjected to conventional BS-treatment as well as oxidative BS (oxBS)-conversion using TrueMethylTM 96 kit of CEGXTM (Cambridge Epigenetix Limited) to allow for subsequent detection of hydroxymethylation (5hmC = BS - oxBS). Overall design: Detection of DNA methylation differences (oxBS, BS and 5hmC) in NeuN+ sorted from white matter brain tissue of MS patients and non-neurological controls
创建时间:
2018-09-05



