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Rapid engineering of SARS-CoV-2 therapeutic antibodies to increase breadth of neutralization including XBB.1.5 and BQ.1.1

NCATS Open Data2023-02-03 更新2026-08-08 收录

抗体工程

SARS-CoV-2中和广度

数据链接：

https://doi.org/10.1101/2023.01.25.525589 数据链接链接失效反馈

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Rapid engineering of SARS-CoV-2 therapeutic antibodies to increase breadth of neutralization including XBB.1.5 and BQ.1.1

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创建时间：

2023-01-26

抗体工程

CD4结合位点

Table S1: Immunization Schedule. Llamas 1 and 3 were immunized via intramuscular injection as indicated in the table. Protein injections were in a freshly prepared 4.5-ml water in oil emulsion prepare

NIAID Data Ecosystem60

Crystal structure of homo-specific diabody

蛋白质晶体

抗体工程

Crystal structure of homo-specific diabody Descriptor: homo-specific diabody protein Authors: Kim, J.H, Song, D.H, Youn, S.J, Kim, J.W, Cho, G, Lee, H, Lee, J.O. Deposit date: 2016-08-12 Release date:

Protein Data Bank Japan2024-10-09 更新60

Antibody titers following amplification of VL/VH fragments using either standard or rh-PCR Gen-2 primers for the nested PCR.

抗体工程

PCR引物

Antibody titers following amplification of VL/VH fragments using either standard or rh-PCR Gen-2 primers for the nested PCR.

NIAID Data Ecosystem30

Llama nanobody n02 raised against EAEC T6SS TssM

结构生物学

抗体工程

Llama nanobody n02 raised against EAEC T6SS TssM Descriptor: Llama nanobody n02 VH domain Authors: Nguyen, V.S, Desmyter, A, Le, T.T.H, Durand, E, Kellenberger, C, Douzi, B, Spinelli, S, Cascales, E,

Protein Data Bank Japan2024-10-16 更新60

Effect of the total galactose content on complement-dependent cytotoxicity of the therapeutic anti-CD20 IgG1 antibodies under temperature stress conditions

抗体工程

生化活性

The degree of monoclonal antibody galactosylation is known to affect complement-dependent cytotoxicity (CDC) activity by affecting C1q binding, suggesting that galactose is associated with CDC bioacti

DataCite Commons2020-08-27 更新60

Rapid engineering of SARS-CoV-2 therapeutic antibodies to increase breadth of neutralization including XBB.1.5 and BQ.1.1

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