five

Crystal structure of SARS-Cov-2 main protease P132H mutant in complex with PF07321332

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Protein Data Bank Japan2025-07-09 更新2026-04-04 收录
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Crystal structure of SARS-Cov-2 main protease P132H mutant in complex with PF07321332 Descriptor: (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, 3C-like proteinase nsp5 Authors: Li, W.W, Zhang, J, Li, J. Deposit date: 2022-12-27 Release date: 2023-12-27 Last modified: 2025-07-09 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Evaluation of the Inhibition Potency of Nirmatrelvir against Main Protease Mutants of SARS-CoV-2 Variants. Biochemistry, 62, 2023
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2022-12-27
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