Hypermethylated gene in single hepatocytes from HBHC enriched in KEGG pathway.

O is the observed gene number in the pathway. E is the expected gene number in the pathway (Expected number of genes in a specific pathway for an interesting gene set = Total number of genes in the pathway for the reference set × Total number of genes in the interesting set/Total number of genes in the reference set). R is the ration of enrichment for the pathway (R = O/E). P is the p value indicating the significance of enrichment calculated from hypergeometric test. It is given for the pathways with R>1.