Asymmetric Total Synthesis of (−)-Linderol A
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https://figshare.com/articles/dataset/Asymmetric_Total_Synthesis_of_-Linderol_A/12063915
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资源简介：
The first asymmetric total synthesis of (−)-Linderol A, a potent inhibitor of melanin biosynthesis of
cultured B-16 melanoma cells, has been achieved via two key reactions: a diastereoselective [2+2]
photocycloaddition of a coumarin-3-carboxylate bearing a chiral auxiliary with 3-methyl-1-butene and a
subsequent stereoconvergent transformation of the photoadducts with use of dimethylsulfoxonium
methylide to afford a tetrahydrodibenzofuran derivative.
创建时间：
2007-07-20
