Patient-derived medullary thyroid cancer in vitro models

the dataset contains: uncropped gels of western blot representative images FASTQ files from NGS targeted sequencing AB1 files from direct Sanger Sequencing (confirmation of RET, RAS, CDKN1B and KIT variants at later passages) Raw data of: PDS size Western blot densitometry Cell types absolute number Calcitonin, Chromogranin A and Thyroglobulin ELISA readout ELDA parameters RT-qPCR cycles MTC IF quantification of whole tissues and of perivascular and invasive ROIs Sphere IF quantification Matrigel invasion assay measurements Zebrafish xenograft angiogenesis and invasiveness quantification Proliferation assays readout for drug dose-response experiments Full correlation values between gene expression and drug effects