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Spliceosome iCLIP in multiple cell lines
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创建时间：
2019-08-03
相关数据集
SRSF2 mutations impair hematopoiesis and alter exon recognition
Mutations within genes encoding spliceosomal proteins are the most common class of mutations in patients with myelodysplastic syndromes, yet it is currently not well understood how these mutations imp
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An uncharacterized gene, C7orf26, identified from an autosomal dominant ocular disease functions in mRNA splicing. An uncharacterized gene, C7orf26, identified from an autosomal dominant ocular disease functions in mRNA splicing
An uncharacterized gene, C7orf26 was expected to function with the integrator complex in mRNA splicing. To address the involvement of mRNA splicing, we performed microarray analysis of HeLa/C7orf26 si
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In the compact mRNPs, CERKL interacts with PABP, HSP70 and RPS3 in an mRNA-dependent manner.
A and B) HEK-293T cells were transfected with CERKL-WT (A) or with CERKL-C125W mutant (B). After 48 h, cells were treated with 100 µg/ml cycloheximide and lysates were treated or not with RNase A (100
Figshare2016-02-23 更新00
PAR-CLIPseq for C-terminal truncated G3BP1 binding RNA
This data aims to screen RNAs that specifically bind to the truncated G3BP1 proteins 259-466aa and 310-466aa, which are different from those binding to the full-length G3BP1. The RNA samples are deriv
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Hydrogen bonds at the binding interface of the Rbfox*•pre-miR20b* complex during simulations.
The average donor-acceptor distances and angles are calculated over the entire simulation ensemble for the trajectory frames in which the individual H-bonds are observed and the interactions are furth
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