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Confirming genotype specific effects for a Parkinsons disease associated variant in induced pluripotent stem cells

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NIAID Data Ecosystem2026-05-10 收录
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We characterised the effects of the rs11610045 genotype in KOLF2.1J iPSCs by integrating CRISPR-Cas9 SNP introduction and reversal, transcriptomics, spatial genomics (Micro-C), long-read whole-genome sequencing for mutational load, and proteomics (AP-MS).

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2026-01-12
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