Effect of anti-mouse TNF and IL-6 antibodies as well as their combination in a collagen-induced arthritis mouse model
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE200292
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Additive effects of anti-TNF and anti-IL-6 were evaluated in a murine collagen-induced arthritis (CIA) model by RNA-seq Collagen-Induced Arthritis was induced in DBA/1 mice by immunizing with chicken type II collagen twice on day 1 and 21. Starting day 21, mice (n=13/group) were treated with either isotype control antibody, anti-TNF antibody, anti-IL-6 antibody, or the combination of the latter twice per week for a total duration of 5 weeks. RNA-seq of whole paw homogenate was performed on day 91
创建时间:
2022-12-31



