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CDC-like Kinase 4 Deficiency Contributes to Pathological Cardiac Hypertrophy by Modulating NEXN Phosphorylation

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NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE188360
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To investigate how sustained NEXN phosphorylation ameliorated the pathological phenotype in Clk4-cKO mice. We performed microarray analysis in the Clk4-cKO myocardium treated with AAV NEXN-S437E, wherein AAV NEXN-WT served as a control. Clk4-cKO myocardium treated with AAV NEXN-S437E, wherein AAV NEXN-WT served as a control. n = 3 animals for each group.
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2022-08-16
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