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Single cell transcriptional profiling of skin from wild type (WT) and Card14KI mice

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We performed single cell RNA sequencing (scRNA-seq) to further analyze the differentially expressed genes in each cell type from WT and Card14KI mice. As a result of scRNA-seq, changes in gene expression were large in granular layer cells, cells in the outer roof sheath and fibroblasts. Single cell suspension of whole skin from WT and Card14KI mice were analyzed using scRNAseq.

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