five

USP1 bound to ML323 and ubiquitin conjugated to FANCD2 (focused refinement)

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Protein Data Bank Japan2024-07-24 更新2026-04-19 收录
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USP1 bound to ML323 and ubiquitin conjugated to FANCD2 (focused refinement) Descriptor: 5-methyl-2-(2-propan-2-ylphenyl)-~{N}-[[4-(1,2,3-triazol-1-yl)phenyl]methyl]pyrimidin-4-amine, Ubiquitin carboxyl-terminal hydrolase 1, Ubiquitin-60S ribosomal protein L40, ... Authors: Rennie, M.L, Walden, H. Deposit date: 2022-04-05 Release date: 2022-10-12 Last modified: 2024-07-24 Method: ELECTRON MICROSCOPY (2.49 Å) Cite: Cryo-EM reveals a mechanism of USP1 inhibition through a cryptic binding site. Sci Adv, 8, 2022
创建时间:
2022-04-05
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