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Crystal structure-based design and disovery of a novel PARP1 antiagonist (BL-PA10) that induces apoptosis and inhibits metastasis in triple negative breast cancer

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Protein Data Bank Japan2024-03-20 更新2026-03-21 收录
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https://pdbj.org/mine/summary/5ha9
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Crystal structure-based design and disovery of a novel PARP1 antiagonist (BL-PA10) that induces apoptosis and inhibits metastasis in triple negative breast cancer Descriptor: Amitriptyline, GLYCEROL, Poly [ADP-ribose] polymerase 1, ... Authors: Fu, L, Peng, H, Zhang, L, Ouyang, L. Deposit date: 2015-12-30 Release date: 2016-03-09 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (4.01 Å) Cite: Crystal structure-based discovery of a novel synthesized PARP1 inhibitor (OL-1) with apoptosis-inducing mechanisms in triple-negative breast cancer. Sci Rep, 6, 2016
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2015-12-30
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