Responses of Atlantic salmon to vaccination and challenge with salmon alphavirus (SAV) and Moritella viscosa

Salmon alphavirus (SAV) and Moritella viscosa causing respectively pancreatic disease and winter ulcer are among the most important pathogens threatening Atlantic salmon aquaculture. Fish is protected by vaccination with different rate of success. Here, responses to vaccination were assessed followed with pathogen challenges of vaccinated salmon and saline injected control. Salmon was smoltified and vaccinated with a commercial multicomponent vaccine according to standard protocols, control group received saline injection. After 9 weeks, fish was challenged by co-habitation with shedders. Tissues samples were collected after respectively 21 dpi (SAV) and 42 dpi (M. viscosa).