Data_Sheet_1_Nomogram to Predict Cognitive Dysfunction After a Minor Ischemic Stroke in Hospitalized-Population.pdf

An easily scoring system to predict the risk of cognitive impairment after minor ischemic stroke has not been available. We aimed to develop and externally validate a nomogram for predicting the probability of post-stroke cognitive impairment (PSCI) among hospitalized population with minor stroke. Moreover, the association of Trimethylamine N-oxide (TMAO) with PSCI is also investigated. We prospectively conducted a developed cohort on collected data in stroke center from June 2017 to February 2018, as well as an external validation cohort between June 2018 and February 2019. The main outcome is cognitive impairment defined as

目前尚无一种易于评分的系统可用于预测轻微缺血性卒中后认知障碍的风险。本研究旨在开发并对外验证一种预测住院轻微卒中患者发生卒中后认知障碍（PSCI）概率的诺模图。此外，还探讨了三甲胺N-氧化物（TMAO）与PSCI之间的关联。我们于2017年6月至2018年2月在卒中中心收集数据，前瞻性地进行了一项队列研究，并在2018年6月至2019年2月期间进行了外部验证队列研究。主要结局为认知障碍，定义为...