First bromodomain of BRD4 in complex with ISOX-DUAL based degrader 35
收藏Protein Data Bank Japan2025-09-24 更新2026-04-19 收录
下载链接：
https://pdbj.org/mine/summary/9f1l
下载链接
链接失效反馈官方服务：
资源简介：
First bromodomain of BRD4 in complex with ISOX-DUAL based degrader 35 Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, N-[2-[2-[(3R)-2,6-bis(oxidanylidene)piperidin-3-yl]-1,3-bis(oxidanylidene)isoindol-4-yl]oxyethyl]-2-[4-[2-[2-[2-[4-[3-(dimethylamino)propoxy]phenyl]ethyl]-5-(3,5-dimethyl-1,2-oxazol-4-yl)benzimidazol-1-yl]ethyl]piperazin-1-yl]ethanamide Authors: Balourdas, D.I, Edmonds, A.K, Marsh, G.P, Maple, H.J, Spencer, J, Knapp, S, Joerger, A.C, Structural Genomics Consortium (SGC) Deposit date: 2024-04-19 Release date: 2024-09-11 Last modified: 2025-09-24 Method: X-RAY DIFFRACTION (1.30000625447 Å) Cite: Structure-Guided Design of ISOX-DUAL-Based Degraders Targeting BRD4 and CBP/EP300: A Case of Degrader Collapse. J.Med.Chem., 68, 2025
创建时间：
2024-04-19
