Validation of potential HSF1 regulators using RNAi.

aMean ± SD for 4 biological replicates.
bStatistical significance between the HSP70B reporter and the TK and CMV reporters was calculated using a two sample t-test. The p-values were corrected for multiple comparisons using false discovery rate. Negative p-values denote a reduction in activity versus the control reporter. SCRAM_1 and SCRAM_2 denote negative RNAi controls. HSF1_1 and HSF1_2 denote positive RNAi controls for the reduction of HSF1 activity.