Maximizing_the_knowledge_gained_from_California_Senate_Bill_27

Overuse of antibiotics contributes to antimicrobial resistance and is a growing threat to human health worldwide. In the U.S., approximately 70% of antibiotics are sold for use in livestock. On January 1, 2018, California enacted Senate Bill 27 (SB27), which will require a veterinarian's prescription for use of antimicrobial drugs and ban non-therapeutic antimicrobial uses for routine disease prevention and growth promotion in livestock. The project will quantify the effect of SB27 on E. coli, Campylobacter and Salmonella resistance rates from retail meat; estimate the proportion of human Campylobacter, Salmonella, and extraintestinal pathogenic E. coli infections caused by strains of food animal origin in California; characterize the effect of SB27 on antimicrobial susceptibility of Campylobacter, Salmonella, and extraintestinal E. coli infections caused by strains of food animal origin in California.