Jejunal long noncoding RNAs are associated with glycemic control via gut-brain axis after bariatric surgery in diabetic mice

To investigate the alterations in the jejunal Roux limb lncRNA expression signatures after DJB and analyze the functional pathways associated with metabolic improvement on a genome-wide scale in high-fat diet (HFD)-induced diabetic mice. Diabetic mice induced by HFD were randomly assigned into two groups undergoing either DJB or sham surgery. The lncRNA and mRNA expression profiles of the Roux limb segment of the jejunum in both groups were investigated using microarray.