Co-crystal structure of Human Farnesyltransferase with farnesyldiphosphate and inhibitor compound 66
收藏Protein Data Bank Japan2023-08-16 更新2026-03-21 收录
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Co-crystal structure of Human Farnesyltransferase with farnesyldiphosphate and inhibitor compound 66 Descriptor: (20S)-19,20,22,23-TETRAHYDRO-19-OXO-5H,21H-18,20-ETHANO-12,14-ETHENO-6,10-METHENOBENZ[D]IMIDAZO[4,3-L][1,6,9,13]OXATRIA ZACYCLONOADECOSINE-9-CARBONITRILE, FARNESYL DIPHOSPHATE, ZINC ION, ... Authors: Taylor, J.S, Terry, K.L, Beese, L.S. Deposit date: 2002-04-08 Release date: 2002-06-19 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2 Å) Cite: 3-Aminopyrrolidinone farnesyltransferase inhibitors: design of macrocyclic compounds with improved pharmacokinetics and excellent cell potency. J.Med.Chem., 45, 2002
创建时间：
2002-04-08
