Macrophages are amongst the first immune cells that encounter rabies virus (RABV) at injured sites, but insights into if and how RABV affects macrophage activation are scarce. We undertook this study

NIAID Data Ecosystem20

Early Notch signaling programs effector CD8+ T cell differentiation [RNA-Seq]. Early Notch signaling programs effector CD8+ T cell differentiation [RNA-Seq]

T细胞免疫调节

Notch信号通路

A better understanding of the mechanisms regulating CD8+ T cell differentiation is essential to develop new strategies to fight infections and cancer. Using genetic mouse models and blocking antibodie

NIAID Data Ecosystem10

Gene regulatory basis of bystander activation in CD8+ T cells (human scRNA-seq). Gene regulatory basis of bystander activation in CD8+ T cells (human scRNA-seq)

T细胞免疫调节

单细胞转录组学

CD8+ T cells have been categorized as an adaptive lymphocyte, based on their ability to recognize specific foreign antigens and mount memory responses. However, neonatal and adult CD8+ T cells are der

NIAID Data Ecosystem30

Systemic inflammation drives rapid conversion of conventional CD4+ T cells to Treg in vivo.

T细胞免疫调节

炎症诱导Treg转化

The immune system faces a task that approximates cognition in its complexity as it processes a multitude of intrinsic and extrinsic signals and integrates these into responses of the appropriate class

NIAID Data Ecosystem20

Adenovirus Serotype 5 Vectors Trigger IL-27-Dependent Inhibitory CD4+ T Cell Responses

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