Complex of Aurora-A bound to an Imidazopyridine-based inhibitor
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Complex of Aurora-A bound to an Imidazopyridine-based inhibitor Descriptor: 6-bromo-2-(1-methyl-1H-imidazol-5-yl)-7-{4-[(5-methyl-1,2-oxazol-3-yl)methyl]piperazin-1-yl}-1H-imidazo[4,5-b]pyridine, AURORA KINASE A, SULFATE ION Authors: Kosmopoulou, M, Bayliss, R. Deposit date: 2012-07-02 Release date: 2013-03-13 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Optimization of Imidazo[4,5-B]Pyridine-Based Kinase Inhibitors: Identification of a Dual Flt3/Aurora Kinase Inhibitor as an Orally Bioavailable Preclinical Development Candidate for the Treatment of Acute Myeloid Leukemia. J.Med.Chem., 55, 2012
创建时间：
2012-07-02
