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Crystal structure of p53 Y220C covalently bound to indole KG10

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Protein Data Bank Japan2024-11-13 更新2026-04-19 收录
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Crystal structure of p53 Y220C covalently bound to indole KG10 Descriptor: 4-[4-(4-methylpiperazin-1-yl)phenyl]-1-(2-methylprop-2-enoyl)-1H-indole-3-carbaldehyde, bound form, Cellular tumor antigen p53, ... Authors: Guiley, K.Z, Shokat, K.M. Deposit date: 2022-06-15 Release date: 2022-10-12 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.98700696061 Å) Cite: A Small Molecule Reacts with the p53 Somatic Mutant Y220C to Rescue Wild-type Thermal Stability. Cancer Discov, 13, 2023
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2022-06-15
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