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Stem cell-derived neutrophil-primed progenitors prevent lethal infection

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NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE156612
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We show that engineered neutrophil-primed progenitors derived from human induced pluripotent stem cells (NeuPs-XL) can produce functional neutrophil-like cells (NeuCs-XL) that can act promptly in vivo against lethal bacterial infections at a clinically applicable scale. We performed global gene expression profiling of NeuPs-XL and NeuCs-XL with or without LPS stimulation. gene expression profiling of NeuPs-XL and NeuCs-XL with or without LPS stimulation
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2023-04-17
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