METHODS AND PLATFORMS FOR SUSTAINABLE HIGH YIELD TERPENOID PRODUCTION
收藏国家林业和草原科学数据中心2023-02-12 更新2024-03-07 收录
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Transgenic plants and methods for terpenoid production leveraging such transgenic plants are provided. Such transgenic plants may comprise a first heterologous nucleic acid encoding a polypeptide having 3-hydroxy-3-methylglutarylCoA reductase activity and a second heterologous nucleic acid encoding a polypeptide that introduces de novo formation of isopentenyl phosphate in the plant. Such de novo IP production may be achieved through the overexpression of phosphomevalonate decarboxylase in conjunction with 3-hydroxy-3-methylglutarylCoA reductase， which can result in up to a 130-fold increase of terpenoid production as compared to a wild-type plant.
提供机构：
国家林业和草原科学数据中心
创建时间：
2023-02-12
