Dataset of 320 novel T cell receptor (TR) alleles identified from 44 HPRC subjects

This dataset is based on high-quality genome assemblies provided by the Human Pangenome Reference Consortium (HPRC), which represent diverse human genomes to ensure comprehensive coverage of genetic diversity. Using the gAIRR Suite (https://github.com/maojanlin/gAIRRsuite), we identified 320 novel T Cell Receptor (TR) alleles from 44 HPRC assemblies. These alleles are categorized into two groups: TRV (T Cell Receptor Variable): Stored in TRV_novel.fasta. TRJ (T Cell Receptor Joining): Stored in TRJ_novel.fasta. Supporting Files: TRV_novel_haplotype_seq.csvSummarizes TRV alleles identified in HPRC subjects, including novel ones. Each row includes the nucleotide sequence of an allele and its corresponding haplotypes (h1 for paternal and h2 for maternal). TRJ_novel_haplotype_seq.csvDetails TRJ alleles identified in HPRC subjects, including novel ones. The file provides the nucleotide sequence for each allele, along with haplotypes (h1 for paternal and h2 for maternal) where it was detected. The genome assemblies were sourced from the official HPRC GitHub repository:https://github.com/human-pangenomics/HPP_Year1_Assemblies. This dataset offers a valuable resource for studying T Cell Receptor diversity and its role in immune function.