Altered expression profile of long non-coding RNA and mRNA in mice cortex around injury focus after traumatic brain injury. Mus musculus

We report the altered expression profiles of lncRNA and mRNA in mice cortex afetr traumatic brain injury (TBI).Total of 27,457 transcripts were identified as mRNA and 37,073 transcripts were identified as lncRNA. Total of 823 lncRNAs and 1,580 mRNAs were significantly changed after TBI according to the criteria: |log2(fold change)|>1, P<0.05. In addition, total of 360 new mRNAs and 8,041 new lncRNAs were identified in current sequencing study. Overall design: TBI was induced in C57BL/6 mice. The LncRNA and mRNA expression profiles in cortex of normal mice and TBI mice were examined by RNA-Seq.