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Disease Severity and Immune Activity Relate to Inter-Kingdom Gut Microbiome States in Ethnically Distinct Ulcerative Colitis Patients

ChEBI2016-07-25 更新2026-07-12 收录

溃疡性结肠炎微生物组学

炎症性肠病精准医疗

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-78724 数据链接链接失效反馈

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资源简介：

Disease Severity and Immune Activity Relate to Inter-Kingdom Gut Microbiome States in Ethnically Distinct Ulcerative Colitis Patients

应用场景：

创建时间：

2016-07-25

炎症性肠病精准医疗

药物反应预测

To pharmacologically assess patient variation in response to IBD treatment, we used the reduction in the release of the inflammatory cytokine TNFα from the fresh IBD tissues in the presence or absence

NIAID Data Ecosystem70

Identification of S100A9 as a target for diagnosis and treatment of Crohn's Disease after Vedolizumab treatment failure

炎症性肠病精准医疗

治疗反应生物标志物

Recent advances in Whole-Transcriptome Sequencing technologies enable the complete sequencing of entire genomes and allow us to analyze a number of disease genome profiles. In our study, whole-transcr

NIAID Data Ecosystem10

Table 6_Individual-network based predictions of microbial interaction signatures for response to biological therapies in IBD patients.xlsx

微生物组治疗

炎症性肠病精准医疗

Inflammatory Bowel Disease (IBD), which includes Ulcerative Colitis (UC) and Crohn’s Disease (CD), is marked by dysbiosis of the gut microbiome. Despite therapeutic interventions with biological agent

NIAID Data Ecosystem00

Cross species transcriptomic signatures predict response to MK2 inhibition in mouse models of chronic inflammation. Cross species transcriptomic signatures predict response to MK2 inhibition in mouse models of chronic inflammation

炎症性肠病精准医疗

转录组生物标志物

Translating observations from preclinical models to patients is one of the most pressing challenges in biomedical research. Part of the challenge derives from the necessity of studying preclinical the

NIAID Data Ecosystem40

Gene expression profiling in Inflammatory Bowel Disease identifies characteristics for anti-TNF-alpha response and targets for alternative therapies

炎症性肠病精准医疗

生物标志物响应

Gene expression profiling in Inflammatory Bowel Disease identifies characteristics for anti-TNF-alpha response and targets for alternative therapies

ChEBI2022-12-31 更新00