CRYSTAL STRUCTURE OF HUMAN PHOSPHODIESTERASE 4D IN COMPLEX WITH A TETRAFLUORANLINE COMPOUND
收藏Protein Data Bank Japan2023-10-04 更新2026-03-21 收录
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https://pdbj.org/mine/summary/5tkb
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CRYSTAL STRUCTURE OF HUMAN PHOSPHODIESTERASE 4D IN COMPLEX WITH A TETRAFLUORANLINE COMPOUND Descriptor: ETHANOL, MAGNESIUM ION, N-[(2R)-2,3-dihydroxy-2-methylpropyl]-8-(methylamino)-6-[(2,3,5,6-tetrafluorophenyl)amino]imidazo[1,2-b]pyridazine-3-carboxamide, ... Authors: Sack, J.S. Deposit date: 2016-10-06 Release date: 2016-12-28 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.16 Å) Cite: Identification of imidazo[1,2-b]pyridazine TYK2 pseudokinase ligands as potent and selective allosteric inhibitors of TYK2 signalling. Medchemcomm, 8, 2017
创建时间:
2016-10-06



