Expression data from murine lymphatic endothelial cells with angiotensin II treated

Proliferation and migration of lymphatic endothelial cells (LECs) are essential for lymphatic vessel growth (also known as lymphangiogenesis), which plays a critical role in regulating the tissue fluid balance and immune cell trafficking in physiological and pathological conditions. In this study, murine LECs were stimulated with Ang II (500 nM) or saline for 12 or 24 hours. Cell proliferation and migration were determined. The gene expression profiles and signaling pathways were detected by time series microarray analysis.