Protein phosphatase 2A propels follicular T helper cell development in lupus

To investigate the difference of gene expression in transcription level between PP2A Ca subunit knockout CD4+ T cell and WT T cell after TCR stimulation, we performed gene expression profiling analysis using data obtained from RNA-seq of the PP2A WT and CKO Naive CD4+ T cell stimulated with plate-bound CD3/CD28 for 1 hour. Overall design: Comparative gene expression profiling analysis of RNA-seq data for PP2A WT and KO TCR stimulated 1 hour CD4+ T cells.