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Crystal structure of VEGFR2 in complex with a 2-anilino-5-aryl-oxazole inhibitor

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Protein Data Bank Japan2024-02-14 更新2026-03-21 收录
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Crystal structure of VEGFR2 in complex with a 2-anilino-5-aryl-oxazole inhibitor Descriptor: N-[5-(ETHYLSULFONYL)-2-METHOXYPHENYL]-5-[3-(2-PYRIDINYL)PHENYL]-1,3-OXAZOL-2-AMINE, Vascular endothelial growth factor receptor 2 Authors: Harris, P.A, Cheung, M, Hunter, R.N, Brown, M.L, Veal, J.M, Nolte, R.T, Wang, L, Liu, W, Crosby, R.M, Johnson, J.H, Epperly, A.H, Kumar, R, Luttrell, D.K, Stafford, J.A. Deposit date: 2004-12-05 Release date: 2005-06-07 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Discovery and evaluation of 2-anilino-5-aryloxazoles as a novel class of VEGFR2 kinase inhibitors. J.Med.Chem., 48, 2005
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2004-12-05
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