Lignocellulosic Inhibitor tolerance

This project was designed to isolate Saccharomyces cerevisiae strains in a screen for improved tolerance to pretreated lignocellulosic biomass inhibitors. These inhibitors are problematic in the efficiency and ultimately cost-effectiveness of using lignocellulosic biomass as a feedstock for the production of fuels and chemicals. Whole genome sequencing of two strains isolated in this screen was undertaken in an effort to potentially understand what genes and/or structural rearrangements could potentially lead to the improved tolerance observed.