10x Lacrimal Gland scRNA seq data matrix

Isolated Lacrimal gland for Single Cell RNA sequence data from E16 and P4 mice. These are the raw read count matrices along side the barcode for the cells and genes that span the sparse matrix. These results are published in Development: Defining epithelial cell dynamics and lineage relationships in the developing lacrimal gland.Abstract:The tear producing lacrimal gland is a tubular organ that protects and lubricates the ocular surface. While the lacrimal gland possesses many features that make it an excellent model to understand tubulogenesis, the cell types and lineage relationships that drive lacrimal gland formation are unclear. Using single cell sequencing and other molecular tools, we reveal novel cell identities and epithelial lineage dynamics that underlie lacrimal gland development. We show that the lacrimal gland from its earliest developmental stages is composed of multiple subpopulations of immune, epithelial, and mesenchymal cell lineages. The epithelial lineage exhibits t...