Phenomenological and thermodynamic parameters for the ATPase activity and Vi-induced trapping of Pgp.
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Compilation of the values reported for some of the parameters that describe the ATPase and Vi trapping properties of Pgp from Chinese hamster ovary cells.P, solubilized Pgp; PM, plasma membrane; Ver, verapamil. Unless otherwise stated, T = 37°C.aMIANS-labeled Pgp;bT = 22°C;cT = 10°C;dCorrected for ionic strength;eTrapping with 200 µM Vi and nucleotide;f5 mM ATP + 2.5 mM Mg2+.
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2015-12-02
