We investigate whether HDAC6 affects STAT3 activation in Colorectal Cancer cells (CCD-841 human colon normal cells, HT29 and HCT116 cells), through treatments with Nexturastat A (NexA), a specific HDA
BackgroundCircular RNAs (circRNAs) have been recently proposed as hub molecules in various diseases, especially in tumours. We found that circRNAs derived from ribonuclease P RNA component H1 (RPPH1)
Surgical excision is currently the principal therapy for locoregional colorectal cancer (CRC). However, surgical trauma leads to controlled tissue damage, causing profound alterations in host immunity
The immune system is crucial in regulating colorectal cancer tumorigenesis. Identification of immune-related transcriptomic signatures derived from the peripheral blood of colorectal cancer patients w