Mutational and transcriptomic landscapes of a rare human prostate basal cell carcinoma

We applied single-cell genomic amplification and RNA-Seq to a specimen of human prostate BCC. The mutational landscape was obtained via whole exome sequencing of the MDA product mixture from 49 single cells, and the transcriptomes of 69 single cells were also obtained by using Fluidigm C1 IFC (10~17 um).