pseudorabies virus intestinal injury and PRV XJ delgE/gI/TK prevention of pseudorabies virus intestinal injury

In this study, the PRV mouse drop-nose infection model was used to screen for differentially expressed genes in the gut among immunization-challenged group, challenged group, and mock groups. The aim of this study was to investigate the mechanisms by which PRV causes intestinal pathogenicity and by which PRV delgE/gI/TK attenuates intestinal damage caused by wild strains. This study has important implications for understanding the mechanisms of PRV damage to the gut and for the development of anti-PRV drugs.