Ligand-Gated Ion Channel database

The Ligand-Gated Ion Channel database provides nucleic and proteic sequences of the subunits of ligand-gated ion channels. These transmembrane proteins can exist under different conformations, at least one of which forms a pore through the membrane connecting two neighbouring compartments. The database can be used to generate multiple sequence alignments from selected subunits, and gives the atomic coordinates of subunits, or portion of subunits, where available.

该配体门控离子通道数据库提供了配体门控离子通道亚基的核酸和蛋白质序列。这些跨膜蛋白可以处于不同的构象状态，其中至少有一种构象形成贯穿膜孔，连接相邻的腔室。该数据库可被用于从选定的亚基生成多重序列比对，并提供亚基（或亚基的一部分）的原子坐标，如有可用。